联系电话:

010-53218327 / 13621101922

海外专家

Experts

Dr. Michèle LEES

国籍:法国
专业: 分子化学
学历:1983 法国Nantes大学取得博士学位
任职:博士生导师;
         EUROFINS 和 C.E.A.I.S.工程专家;
          欧盟标准、测量和检验议案提交分析专家

          第六届欧盟NEST框会议议案提交分析专家;
          法国国家果汁联盟科学技术委员会成员;
          北美果汁企业联盟协会果汁和果汁产品技术委员会成员;
          欧盟基金调查员
0.00
0.00
  

国籍:法国
专业: 分子化学
学历:1983 法国Nantes大学取得博士学位
任职:博士生导师;
         EUROFINS 和 C.E.A.I.S.工程专家;
          欧盟标准、测量和检验议案提交分析专家

          第六届欧盟NEST框会议议案提交分析专家;
          法国国家果汁联盟科学技术委员会成员;
          北美果汁企业联盟协会果汁和果汁产品技术委员会成员;
          欧盟基金调查员

学历:1983 法国Nantes大学取得博士学位
专业: 分子化学
课题:1982 法国Nantes大学取得DEA
   1976 专业 纯化学和应用化学
语言: 双语(熟练运用英语和法语)略知西班牙语

专业背景
1990-至今 法国Eurofins Scientific, Rue P.A. Bobierre, Site de la Géraudière, 44323 Nantes France
* EUROFINS 和 C.E.A.I.S.工程专家-主要是葡萄酒同位素数据库
* 科学技术合作组织成员
* 1997年担任合作组织的主任
* 现在管理Eurofins Nantes实验室合作研究和发展组织和实验室国际合作计划,全球现在有50多个合作机构。
* 从2001年组织两年一度的食品保真国际会议。
1982 - 1989 GAZ DE FRANCE - LNG (Liquefied Natural Gas) Terminal, Montoir-de-Bretagne, France液化天然气终端
* 向国际公共关系部提供技术支持
* 组织培训顾客
1978 - 1982 Lecturer - Organic Chemistry Laboratory, University of Nantes
1978-1982 Nantes大学有机化学实验室讲师

专业活动
1. 欧盟标准、测量和检验议案提交分析专家。1997年1月
2. 第六届欧盟NEST框会议议案提交分析专家,远程评估和会议成员。
3. 成员“Groupe de Chimie, Physicochimie et Biochimie des Aliments et du Goût”, coordinator Hervé This, Collège de France.
4. 国家果汁联盟科学技术委员会成员
5. 果汁和果汁产品技术委员会成员,北美果汁企业联盟协会
6. 英国软饮料协会果汁控制计划技术专业
7. Co-coordinator : Club 09 - Authenticité, Qualité et Sécurité des Aliments, Cercles des Sciences Analytiques, affilié à la Société Française de Chimie.
INVOLVEMENT IN EU-FUNDED RESEARCH,欧盟基金调查员

协调参加以下计划
* 橄榄油分子和同位素分析- AIR-CT94-1224 1/12/94-30/11/97
* 食品保真技术- AIR3-CT94-2452 1/01/94-31/12/97
* 利用同位素技术分析食品- SMT4-CT95-7500 1/01/96-31/12/98
* 制定食品和酒类产品保真体系同位素领域参考SMT4-CT96-2086 1/09/96-31/08/99
* 检测葡萄酒中甘油-比对和认证现存的方法GCRD-CT-2000-00416, 01/01/2001-31/12/2002
* 果汁分析新标准:和HPLC技术检测结合- SMT4-CT97-2206 1/02/98-31/01/00
* 鉴别野生和驯养鲑鱼和其他鱼的方法G6RD-CT-2001-005412 , 01/09/2001-31/08/2004
* 气相和同位素质谱连用的参照物G6RD-CT-2001-00515, 01/09/2001-31/03/2004
* 检测鉴别假冒药品G6RD-CT-2002-00849, 01/01/2003-31/12/2005

以下计划中的科学技术负责人:
满足工业常规分析需要的生物传感器- SMT4-CT96-2086 1/09/96-31/08/99;
利用同位素质谱检测果汁中糖18O/16O值- SMT4-CT98-2219 1/05/98-30/04/00;
牛奶、黄油和奶酪检测方法的开发和确立- SMT4-CT98-2236 1/10/98-30/09/01;
建立和认证分析鉴别榛实油的方法– G6RD-CT-2000-0040 1/01/2000-2/12/2003;
建立第三国家葡萄酒分析参数的数据银行– GRD2-2000-31812, 01/04/2002 – 31/03/2005;
纯果汁:同位素和微量组分分析G6RD-CT-2002-00760, 01/07/2002-30/06/2005。

其他领域
* Modern analytical methods for food and beverage authentication. Organisation of High-Level Scientific Conferences under the Human Potential Programme funded by the European Commission DG Research. Two conferences organised in Lednice, Czech Republic, September 2000 and 2002.
* 现代食品和酒类产品保真技术分析方法。组织欧盟建立的人类潜能计划下高水平科学会议,两次会议在捷克召开,2000年和2002年。


监督工作,R&D SUPERVISORY ACTIVITIES
博士生导师,Host industry supervisor for doctoral students (government grant)
Marion Cuny, Institut National Agronomique Paris Grignon
Doctoral Thesis in preparation (due April 2008)
Subject: Authentification des produits alimentaires grâce à la spectroscopie RMN du proton et d’outilschimiométriques
Sébastien Guiet, Université de Nantes
Doctoral Thesis obtained February 2004
Subject : Le fractionnement isotopique des acides gras étudié par RMN du deutérium et son application à l’authentification des matières grasses de diverses origines.
Fabienne Bensaid, Institut National Agronomique Paris Grignon
Doctoral Thesis obtained July 2003
Subject : Développement de nouvelles méthodologies fondées sur l’utilisation conjointe de techniques analytiques physico-chimiques et isotopiques pour tracer l’origine de produits alimentaires et pharmaceutiques. Cas de la vanilline, de l’aspirine et du paracétamol.
Alain Royer, Université de Nantes
Doctoral Thesis obtained July 1998
Subject : Authentification de l'origine des huiles d'olive par techniques chromatographiques et isotopiques

发表文章
Dairy product authentication by 1H NMR spectroscopy in combination with different chemometric tools
Cuny, M., Vigneau, E., Lees, M. and Rutledge, D.N., Proceedings of The 8th International Conference on “The application of Magnetic Resonance in Food Science”, July, 2006, Nottingham, UK.
利用1H NMR质谱和化学方法对奶制品保真

Analytical detection of dilution of direct juices.
Jakob, E., Jamin, E., Bitea, C., Lees, M., Fruit Processing, 1:35-39, 2006.
鉴别分析稀释果汁

Quantitation of the main constituents of some authentic sesame seed oils of different origin.
Crews C., Hough P., Godward, J., Brereton, P., Lees, M., Guiet, S., Winkelmann, W., J. Agric. Food Chem. 54:6266-6270, 2006.
定量鉴别来源于特定不同产地的芝麻油中的主成分

Quantitation of the main constituents of some authentic grape-seed oils of different origin.
Crews C., Hough P., Godward, J., Brereton, P., Lees, M., Guiet, S., Winkelmann, W., J. Agric. Food Chem. 54:6261-6265, 2006.
定量鉴别来源于特定不同产地的葡萄籽油中的主成分

Study of the influence of alcoholic fermentation and distillation on the oxygen-18/oxygen-16 isotope ratio of ethanol.
Monsallier-Bitea, C., Jamin, E., Lees, M., Zhang, B.L., and Martin, G.J. J. Agric. Food Chem., 54:279-284, 2006
研究发酵和蒸馏过程对乙醇中18O/16O值的影响

Analytical detection of dilution in direct juices
Jakob, E., Jamin, E., Bitea, C. and Lees, M. Fruit Processing 1:35-39, 2006.
鉴别分析稀释果汁

Study of the main constituents of some authentic hazelnut oils.
Crews C., Hough P., Godward, J., Brereton, P., Lees, M., Guiet, S., Winkelmann, W., J. Agric. Food Chem., 53:4843-4852, 2005.
定量鉴别来源于特定不同产地的榛果油中的主成分

Study of the main constituents of some authentic walnut oils.
Crews C., Hough P., Godward, J., Brereton, P., Lees, M., Guiet, S., Winkelmann, W., J. Agric. Food Chem., 53:4853-4860, 2005.
定量鉴别来源于特定不同产地的胡桃油中的主成分

Chemometrical exploration of an isotopic ratio data set of acetylsalicylic acid
Stanimirova, I., Saszykowski, M., Van Gyseghem, E., Bensaid, F.F., Lees, M., Massart, D.L., Vander Heyden, Y. Analytical Chimica Acta 552, 1 – 12, 2005.
同位素分析乙酰水杨酸

Detection of Exogenous Citric Acid in Fruit Juices by Stable Isotope Ratio Analysis
Jamin, E., Martin, F., Santamaria-Fernandez, R. and Lees, M.
J. Agric. Food Chem. 53(13) 5130 – 5133, 2005
利用稳定同位素分析果汁中外加柠檬酸

Isotopic analysis of lipids as a mean of authenticating fish products.
Thomas, F., Jamin, E. and Lees, M. Lipid Technology 17: 204-208, 2005.
同位素法测定脂类物质鉴别鱼的真实性

Application of multi-element stable isotope ratio analysis to the characterisation of French, Italian and Spanish cheeses,
Camin, F., Wietzerbin, K., Blanch Cortes A.I., Haberhauer G., Lees, M., Versini, G., J. Agric. Food Chem, 52:6592-6601, 2004.
利用多种稳定性同位素分析法国、意大利和西班牙奶酪特征

Quantitative 2H-NMR analysis of deuterium distribution in petroselenic acid isolated from parsley seed.
Guiet, S., Robins, R., Lees, M. and Billault, I., Phytochemistry, 64, 227-233, 2003.
利用2H-NMR定量分析荷兰芹中岩芹酸中D的分布

Improved detection of added water in orange juice by simultaneous determination of the oxygen-18/Oxygen-16 isotope ratios of water and ethanol derived from sugars.
Jamin, E., Guérin, R., Rétif, M., Lees, M., and Martin, G.J., J. Agric. Food Chem., 51 (18), 5202-5206, 2003.
同时测定果汁中水和乙醇中18O/16O值改进原来检测橘子汁中外加水的方法

Part II Authenticating and tracing particular foods : Meat and meat products.
Lees, M. and Pöpping, B. in “Food Authenticity and Traceability”, p. 347-356, Ed. M. Lees, Woodhead Publishing Ltd., Cambridge, UK, 2003.
一些食品的保真和溯踪技术:肉和肉制品

Contrôle et authentification des produits à base de fruits et de légumes et des boissons alcoolisées.
Martin, M.L., Lees, M. et Hanote, V. , in “Fraudes alimentaires - Approche réglementaire et méthodologie analytique
Collection Sciences et techniques agroalimentaires”, Ed. C. J. Ducauze, Tec & Doc, Paris, France, 2003.
''SoftCRM'': A new Software for the Certification of Reference Materials
Bonas, G., Zervou, M., Papaeoannou, T. and Lees, M. Accreditation and Quality Assurance, 8:101-107 (2003)
新的证明参照物的软件

Detection of added L-malic acid in apple and cherry juices – site-specific 13C-IRMS method
Jamin, E., Lees, M., Fuchs, G. and Martin, G., Fruit Processing, 11/2000, 434-436, 2000.
利用特定位点13C-IRMS检测苹果和樱桃汁中外加L-苹果酸

Stable isotope characterisation of olive oils. I – Compositional and carbon-13 profiles of fatty acids.
Royer, A., Gerard, C., Naulet, N., Lees, M. and Martin, G.J. JAOCS, 76, (3), 357-363, 1999.
橄榄油中稳定性同位素特性:脂肪酸中C-13特性

Stable isotope characterisation of olive oils. II – Deuterium distribution in fatty acids studied by nuclear magnetic resonance.
Royer, A., Naulet, N., Mabon, F., Lees, M. and Martin, G.J. JAOCS, 76, (3), 365-373, 1999.
橄榄油中稳定性同位素特性:利用NMR测定脂肪酸中D的分布

Fruit Juices, Nectars and Purées
Lees, M., Martin, G.G., Holland, J. and Branch, S. in “Food Authenticity : Issues and Methodologies”, p. 121-165, Ed. M. Lees, Eurofins Scientific, Nantes, France, 1998.
果汁,酒和

Interpretation of combined SNIF-NMR and 13C SIRA MS analyses of fruit juices to detect added sugar.
Martin G.G., Hanote V., Lees M., and Martin Y.L., Journal of AOAC International, 79(1), 62-72, 1996
利用SNIF-NMR和13C SIRA MS技术分析果汁中外加糖

Stable Isotope Fractionation in Fruit Juice Concentrates : Application to the Authentication of Grape and Orange Products.
Yunianta, Zhang B.L., Lees M. and Martin G.J., J. Agric. Food Chem., 43, 2411 - 2417, 1995.
稳定性同位素分馏法在果汁浓缩汁中的应用:在葡萄和橘子制品中的应用

Authenticity of fermented beverages.
Martin G.G., Symonds P., Lees M. and Martin M.L., in « Fermented Beverages Production », p. 386 -412, Ed. A. Lea and J. Piggott, Blackie Academic & Professional, London, 1995.
发酵酒类产品的保真技术

Application de la RMN du deutérium et carbone-13 à la distinction des arômes naturels et synthétiques : cas de la vanilline, du benzaldehyde et de l’anéthole.
Martin G.J. and Lees M., Office International de la Vigne et du Vin, FV N°962, 1994.
Détection de l’enrichissement des vins par concentration des moûts au moyen de l’analyse isotopique 2H et 18O de l’eau des vins.
Martin G.J. and Lees M., Office International de la Vigne et du Vin, FV N°1019, 1994.
Authentication of Orange Juice.
Fry, J., Martin G.G., and Lees M., in « Production and Packaging of non-carbonated fruit juices and beverages » 2nd Edition, p. 1-51, Ed. P.R. Ashurst, Blackie Academic and Professional, London, 1994.
橘子汁保真技术

Authentification des vins et des produits de la vigne par l’utilisation conjointe des analyses élémentaire et isotopique.
Martin G.J., Zhang B.L., Day M.P., and Lees M., Office International de la Vigne et du Vin, FV N°917, 1993.

博士学位发表的相关文章,Publications from PhD Thesis :
Fragmentation “retro Diels-Alder” de dérivés chlorés à partir de méthylène-2 dihydro-3,6 2H thiazines-1,3.
Lees, M., Boussoufi, M., Bakasse, M., Nourrisson, G. et Duguay, G., Sulfur Letters, 8(3), 147-152, 1988.
Total synthesis of N-protected 7-amino-7-methoxy cephems.
J. Chem. Soc., Chem. Commun., 157-158, 1984.
Dérivés a-méthoxylés de N-acyl cyano-2 glycinates d’alkyle.
Chehna, M., Lees, M., Riahi, M.A., Bujoli, B., Duguay, G. et Quiniou, H., C.R. Acad. Sc. Paris, t. 297, Série II, 663-666, 1983.
Simple and efficient methoxylation of 1,3-dihydrothiazine derivatives.
Riahi, M.A., Lees, M., Chehna, M., Duguay, G. and Quiniou, H. J. Chem. Soc., Chem. Commun., 393-395, 1983.
Addition of organometallics to a,b-unsaturated thiocarbonyl compounds. III. Michael addition of active methylene compounds to thioamide dithiocarbamate vinylogues.
Guémas, J.P., Lees, M., and Reliquet, A. Phosphorus and Sulfur, 17, 307-316, 1983.
Addition of organometallics on a,b-unsaturated thiocarbony compounds. II. Michael addition of lithium enolates on thioamide and dithiocarbamate vinylogs and thioaroylformamidine.
Guémas, J.P., Lees, M., Reliquet, A. and Villieras, J. Phosphorus and Sulfur, 12, 325-339, 1982.
Action d’organométalliques sur les composés thiocarbonylés a,b-insaturés I. Alkylation et hydrolyse des composés d’addition 1,4 d’organométallqieus sur les vinylogues de thioamides et de dithiocarbamates.
Guémas, J.P., Lees, M., Reliquet, A., Reliquet, F. et Quiniou, H., Phosphorus and Sulfur, 8, 351-358, 1980.

书籍,Books
Editor of Food Authenticity and Traceability published by Woodhead Publishing Ltd and CRC Press LLC, 2003, Cambridge, UK (ISBN 1-85573-526-1).
食品保真和溯踪

Editor of Food Authenticity: Issues and methodologies, published in-house by Eurofins Scientific on behalf EC funded Concerted Action, 1998, Nantes, France (ISBN 2-9572051-0-4).
食品保真:原理和方法

CONFERENCES – PRESENTATIONS – TRAINING COURSES (last 3 years)
会议-介绍-培训课程(持续3年)

Ups and downs of the last 12 months in the fruit juice industry
WORLD JUICE 2006, Eurofins Juice Technical Forum, October 19, 2006 Barcelona, Spain
前后至少12个月在果汁企业

Introduction to the Counterpharm project financed by the European Commission.
Jornada de Informação para a Indústria, “Protecção de Substâncias Activas e Intermediários”, 5 April 2006, INETI, Lisbon.
加入欧盟计划基金组织

The international and economic context of counterfeiting and patent infringement for the pharmaceutical and fine chemical industries
Protection of active ingredients and intermediates information da, ESPCI, Paris, 24 November 2005.
国际经济造假和专利侵害

Development and validation of methodology for the confirmation of the origin of wild and farmed salmon and other fish.
开发和验证鉴别野生和驯养鲑鱼和其他鱼的方法

Food Standards Agency Authenticity Programme Research Seminar: development of methodology for traceability and origin, London, 9 March 2005
食品标准局保真计划研究专题讨论会:原产地溯踪

Fruit Juice Authenticity
Leatherhead International Soft Drinks Manufacture Training Course, October 26, 2005, Leatherhead, UK.
果汁保真

L’authenticité.
Produits de la mer : bien choisir sa matiere premiere, Rennes 18 – 19 mai 2005.
Isotopic profiling in food authenticity.
Second International Symposium on "Recent Advances In Food Analysis", Prague, Czech Republic, November 2-4, 2005.
同位素在食品保真中的应用

Exemples de la Recherche et Développement européen : témoignage du secteur des biotechnologies.
Ecole de l’Europe des Pays de la Loire, April 30, 2004, Nantes, France.
Isotopic Analysis of Fruit Juice Components.
Workshop: “Juicy Details”, Technical Committee for Juice and Juice Projects, March 25, 2004, Lake Alfred, Florida, USA
果汁中同位素的组成分析

Fruit Juice Authenticity
Leatherhead International Soft Drinks Manufacture Training Course, October 27, 2004, Leatherhead, UK.
Analytical checks to help the manufacturer meet his obligations in the areas of authenticity of raw materials, fruit content of finished products, pesticide residues and other contaminants.
Conference of the European Industries Transforming Fruit and Vegetables (OEITFL), January 30, 2004, Paris, France.
帮助生产者在在产品原材料、成品中果汁含量和农药以及其他污染物等履行义务,

The contribution of stable isotope analysis to detect counterfeit pharmaceuticals and identify cases of patent infringement. M. Lees, F. Bensaid, G.J. Martin. 2nd Conference of European Customs Chemists, Prague, Czech Republic, October 22 – 24 2003.
利用稳定性同位素技术鉴别造假和专利侵害等。

A multi-element multi-component isotopic approach to the authentication of alcoholic beverages.
International Workshop on Beverage Alcohol Authentication, June 1-4, 2003, Ottawa, Canada.
多元素多成分分析酒精饮料真实性

Measurement of Fruit Content in Foods - A Review
QUID (Quantitative Ingredient Declaration) Network Meeting, March 28, 2003, Barcelona, Spain.
食品中水果测定-综述

The contribution of stable isotope analysis to detect counterfeit pharmaceuticals and identify cases of patent infringement.
2nd Conference of European Customs Chemists, October 22-24, 2003, Prague, Czech Republic.
利用稳定性同位素技术鉴别造假和专利侵害等。

Fruit Juice Authenticity
Leatherhead International Soft Drinks Manufacture Training Course, October 29-30, 2003, Leatherhead, UK.
果汁保真

Traceability : Tracking, Tracing, Labelling. The role of food laboratories.
New and emerging issues for Food Laboratories, Food Safety Authority Ireland, December 9, 2003, Dublin, Ireland.
溯踪:跟踪、溯源、贴标。食品实验室规定

An Update of Juice Authenticity Issues
The British Fruit Juice Association Annual Symposium, June 18, 2003, London, UK.
果汁保真的更新

Authenticity Of Wines And Spirits
Local Authorities Update - Food Safety Surveys and Seminars, October 23, 2002, London, UK.
葡萄酒和蒸馏酒产品保真

Meeting the Analytical Requirements of Codex Standards and the Fruit Juice Directive.
FoodNews World Juice Conference, October 14-16, 2002.
标准分析要求和果汁指令

Himalayan Honey – Who can tell ?
UK FSA, The Leeds Food Standards Update Course, May 20-23, 2002, Leeds, UK.
喜马拉雅山的蜂蜜-谁能说?

Recent developments in Fruit Juice Authenticity Control.
42nd International Fruit Juice Week, April 10-12, 2002, Leipzig, Germany.
果汁真实性保真控制的发展

Fruit Juice Authenticity – Past, Present and Future
FoodNews, World Juice, October 9-11, 2001, Amsterdam, Netherlands.
果汁保真-过去、现在和未来

The use of SNIF NMR® to detect economic fraud
53rd Annual Meeting of the South Eastern Region of the American Chemical Society, September 23-26, 2001, Savannah, Georgia, USA.
利用SNIF-NMR®鉴别经济欺骗

食品真实性技术研究中心

地址:北京市朝阳区酒仙桥中路

   24号院6号楼

Email:FaitLabs@gmail.com

电话:010-53218327

传真:010-53218325

联系人:钟其顶